U.S. President Donald Trump pulled out of Iran's 2015 nuclear deal with world powers a year ago and reimposed sanctions on Tehran, dealing a blow to the country's economy.
"The United States does not have the courage to shoot a single bullet at us despite all its defensive and military assets".
Following reports of a second failed space launch by Iran in less than a month, the U.S. State Department last week called for "tougher global restrictions to deter Iran's missile program". "40 Years of Failure to destabilize Iran through blood & treasure", FM Zarif wrote in a tweet on Tuesday.
"40 years of corruption". 40 Years of Failure to adjust U.S. policy to reality.
Iran even holds an annual "Death to America" rally every November to commemorate the seizure of the U.S. Embassy in 1979, leading to a 444-day hostage crisis in which the Iranian regime held 52 Americans prisoner.
'The long-suffering Iranian people deserve a much brighter future, ' he added.
Israeli Prime Minister Benjamin Netanyahu warned Iran that this year could be the last time it celebrates the anniversary if it attacks his country.
The scathing slogans appeared just days after Iran's supreme leader Ayatollah Ali Khamenei said such insults should not be taken personally by USA or Israeli citizens.
Hundreds of thousands of soldiers, militia members in camouflage fatigues, clerics, and ordinary citizens flocked to the streets of other Iranian cities and towns to commemorate February 11, 1979, when followers of Ayatollah Ruhollah Khomeini ousted a US -backed monarch, Shah Reza Pahlavi.
Newborn baby found lying on road with umbilical cord still attached
The newspaper carrier discovered the baby a short time later and brought her into a vehicle to keep her warm. He initially thought it was an animal until he got closer before realising it was a newborn baby.
But despite the official festivities today's Islamic republic faces acute economic challenges as it struggles with a mix of domestic hardships and United States sanctions.
Iranians march towards Azadi Square during Monday's rally.
But efforts to burn American and Israeli flags were hindered by torrential rain.
Iranian proxies in the region include the Lebanon-based Hezbollah, several terror groups in Gaza, and Shiite militias in Iraq.
Those who took to the streets were bullish despite the economic problems in the country, made worse by Washington's punitive measures.
That April, the Islamic Republic of Iran was proclaimed following a referendum.
"We are here to support the revolution", the 57-year-old pensioner, who refused to give his first name, told AFP at the event in Tehran.
Some of the protesters burned USA flags.
He said: "I came today to defend the ideals of the revolution". Iran's 1979 Islamic Revolution initially inspired both Islamic militants and Islamists across the Mideast.